Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922696 | 0.87 | PPARG (0.64) | ALDH1A1PPARGDRD4TP53 | |
| SCHEMBL9005904 | 0.81 | DRD4 (0.46) | PPARGDRD4TP53KMT2AMEN1 | |
| SCHEMBL7920692 | 0.81 | PPARG (0.50) | PPARGKMT2A | |
| SCHEMBL7926603 | 0.81 | PPARG (0.50) | PPARG | |
| SCHEMBL9005955 | 0.80 | ALOX5 (0.47) | PPARGDRD4TP53KMT2ALMNA | |
| SCHEMBL9005926 | 0.80 | PPARG (0.76) | PPARG | |
| SCHEMBL7920667 | 0.79 | PPARG (0.42) | ALDH1A1PPARGDRD4KMT2ALMNA | |
| SCHEMBL2786491 | 0.79 | PPARG (0.53) | PPARGDRD4 | |
| SCHEMBL9160316 | 0.78 | PPARG (0.42) | PPARGDRD4TP53KMT2ALMNA | |
| SCHEMBL7922719 | 0.78 | PPARG (0.48) | PPARGDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541205-A | ANTIINFLAMMATORY AGENTS; ANTIASTHMA AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-07-30 | — | — | US | claimed |
| US-5428048-A | Aryl-N-hydroxyureas as inhibitors of 5-lipoxygenase and anto-arteriosclerotic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-06-27 | — | — | US | claimed |