Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005955 | 0.90 | ALOX5 (0.47) | PPARGDRD4SMN1; SMN2PPARALMNA | |
| SCHEMBL7922719 | 0.82 | PPARG (0.48) | PPARGDRD4PPARA | |
| SCHEMBL9005904 | 0.81 | DRD4 (0.46) | PPARGDRD4SMN1; SMN2LMNATP53 | |
| SCHEMBL7926603 | 0.81 | PPARG (0.50) | PPARGPPARA | |
| SCHEMBL2786491 | 0.79 | PPARG (0.53) | PPARGDRD4PPARA | |
| SCHEMBL7922696 | 0.79 | PPARG (0.64) | PPARGDRD4TP53 | |
| SCHEMBL9005930 | 0.78 | ALDH1A1 (0.50) | PPARGDRD4LMNATP53SLC40A1 | |
| SCHEMBL4744464 | 0.78 | ATP4A (0.45) | DRD4SMN1; SMN2LMNATP53CETP | |
| SCHEMBL9160339 | 0.77 | PPARG (0.67) | PPARGPPARA | |
| SCHEMBL7920692 | 0.77 | PPARG (0.50) | PPARGPPARAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428048-A | Aryl-N-hydroxyureas as inhibitors of 5-lipoxygenase and anto-arteriosclerotic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |