Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085315 | 0.74 | MAPK14 (0.42) | HMGCRMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7088083 | 0.74 | MAPK14 (0.43) | HMGCRMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL9005999 | 0.72 | MAPK14 (0.46) | MAPK14MAPK13MAPK12MAPK11FAAH | |
| SCHEMBL7090794 | 0.72 | MAPK14 (0.43) | HMGCRMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL11175120 | 0.71 | MAPK14 (0.59) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7084443 | 0.71 | PTGS2 (0.43) | — | |
| SCHEMBL9791608 | 0.69 | FAAH (0.45) | FAAH | |
| SCHEMBL11178939 | 0.69 | PTGS2 (0.38) | — | |
| SCHEMBL10998182 | 0.68 | KDM4E (0.40) | — | |
| SCHEMBL11083061 | 0.66 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736013-A1 | N-SUBSTITUTED ARYL TRIFLUOROMETHYL IMIDAZOLES | BAYER AG (DE) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017390-A1 | N-SUBSTITUTED ARYL TRIFLUOROMETHYL IMIDAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-06-29 | — | — | WO | disclosed |