Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 4/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.58 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.58 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.58 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006476 | 0.90 | MAPT (0.69) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL31549898 | 0.83 | MAPT (0.60) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL3258196 | 0.81 | MAPT (0.58) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL30477506 | 0.81 | MAPT (0.78) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL4120846 | 0.81 | MAPT (0.58) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL11318820 | 0.81 | MAPT (0.78) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL4908405 | 0.81 | MAPT (0.78) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL4120849 | 0.81 | MAPT (0.58) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL4908401 | 0.81 | MAPT (0.78) | MAPTRAB9ANPC1LMNABCHE | |
| SCHEMBL29569445 | 0.81 | MAPT (0.62) | MAPTRAB9ANPC1LMNABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824610-A | A kind of chalcone derivative, preparation method and application containing quinoxaline | 贵州大学 | 2019-05-31 | — | — | CN | disclosed |