SCHEMBL4120846

SCHEMBL4120846

C=Cc1ccccc1/C=C/C(=O)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.58
RAB9A P51151 6/20 0.58
NPC1 O15118 5/20 0.58
BCHE P06276 3/20 0.58
LMNA P02545 2/20 0.58
MAOB P27338 3/20 0.58
CYP1B1 Q16678 2/20 0.58
PLIN1 O60240 1/20 0.58
TNFRSF1A P19438 1/20 0.58
ACHE P22303 1/20 0.58
RECQL P46063 1/20 0.58
PLIN5 Q00G26 1/20 0.58
ABHD5 Q8WTS1 1/20 0.58
KMT2A Q03164 4/20 0.55
ALDH1A1 P00352 4/20 0.55
HPGD P15428 4/20 0.55
MEN1 O00255 3/20 0.55
NFKB1 P19838 3/20 0.55
NFKB2 Q00653 3/20 0.55
RELA Q04206 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3258196 1.00 MAPT (0.58) MAPTRAB9ANPC1BCHELMNA
SCHEMBL4120849 1.00 MAPT (0.58) MAPTRAB9ANPC1BCHELMNA
SCHEMBL9006476 0.90 MAPT (0.69) MAPTRAB9ANPC1BCHELMNA
SCHEMBL31549898 0.83 MAPT (0.60) MAPTRAB9ANPC1BCHELMNA
SCHEMBL9817843 0.82 NFKB1 (0.62) MAPTLMNANFKB1SMN1; SMN2KDM4E
SCHEMBL175543 0.82 NFKB1 (0.62) MAPTLMNANFKB1SMN1; SMN2KDM4E
SCHEMBL1499959 0.82 RAB9A (0.59) MAPTRAB9ANPC1BCHELMNA
SCHEMBL28301997 0.81 MAPT (0.58) MAPTRAB9ANPC1BCHELMNA
SCHEMBL29569445 0.81 MAPT (0.62) MAPTRAB9ANPC1BCHELMNA
SCHEMBL30921141 0.81 AKT1 (0.58) MAPTRAB9ANPC1BCHELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150290588-A1 SIGNAL RESPONSIVE SOLUTES MCGINNIS ROBERT (US) 2015-10-15 US claimed
EP-2928586-A1 SIGNAL RESPONSIVE SOLUTES McGinnis, Robert (US) 2015-10-14 EP claimed
WO-2014089142-A1 SIGNAL RESPONSIVE SOLUTES MCGINNIS ROBERT (US) 2014-06-12 WO claimed
US-7550136-B2 Photo-reactive polymers and devices for use in hair treatments UNIVERSITY OF MASSACHUSETTS (US) 2009-06-23 US claimed
EP-1575537-A4 PHOTO-REACTIVE POLYMERS AND DEVICES FOR USE IN HAIR TREATMENTS UNIV MASSACHUSETTS (US) 2009-02-18 EP claimed
EP-1575537-A2 PHOTO-REACTIVE POLYMERS AND DEVICES FOR USE IN HAIR TREATMENTS University of Massachusetts (US) 2005-09-21 EP claimed
US-20040206368-A1 Photo-reactive polymers and devices for use in hair treatments UNIVERSITY OF MASSACHUSETTS 2004-10-21 US claimed
WO-2004058187-A2 PHOTO-REACTIVE POLYMERS AND DEVICES FOR USE IN HAIR TREATMENTS UNIVERSITY OF MASSACHUSETTS (US) 2004-07-15 WO claimed
US-5484821-A PHOTOCROSSLINKED UNIVERSITY OF LOWELL (US) 1996-01-16 US claimed
US-5290824-A Stilbene, azomethine and disazo dyes, polyvinyl cinnamate, polyvinylstyryl acrylate or polyvinyl chalcone polymer matrix UNIVERSITY OF LOWELL (US) 1994-03-01 US claimed
US-5112881-A Chromogens reacted into crosslinkable polymer, three-dimensional network UNIVERSITY OF LOWELL (US) 1992-05-12 US claimed
US-20150321149-A1 SELECTIVE MEMBRANES FORMED BY ALIGNMENT OF POROUS MATERIALS NAGARE MEMBRANES, LLC 2015-11-12 US disclosed
US-20150290588-A1 SIGNAL RESPONSIVE SOLUTES MCGINNIS ROBERT (US) 2015-10-15 US disclosed
EP-2928586-A1 SIGNAL RESPONSIVE SOLUTES McGinnis, Robert (US) 2015-10-14 EP disclosed
WO-2014100412-A1 SELECTIVE MEMBRANES FORMED BY ALIGNMENT OF POROUS MATERIALS MCGINNIS ROBERT (US) 2014-06-26 WO disclosed
EP-1575537-A2 PHOTO-REACTIVE POLYMERS AND DEVICES FOR USE IN HAIR TREATMENTS University of Massachusetts (US) 2005-09-21 EP disclosed
US-6828409-B2 Branched optical polymers; nonlinear response ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2004-12-07 US disclosed
US-20040206368-A1 Photo-reactive polymers and devices for use in hair treatments UNIVERSITY OF MASSACHUSETTS 2004-10-21 US disclosed
WO-2004058187-A2 PHOTO-REACTIVE POLYMERS AND DEVICES FOR USE IN HAIR TREATMENTS UNIVERSITY OF MASSACHUSETTS (US) 2004-07-15 WO disclosed
US-20040030059-A1 Host-guest polymer system comprising polymer having isoimide group and organic chromophore, side-chain nonlinear optical polymer derived from the same, and method for synthesizing side-chain nonlinear optical polymer ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTIT (KR) 2004-02-12 US disclosed