Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221623 | 0.89 | — | — | |
| SCHEMBL12309038 | 0.89 | — | — | |
| SCHEMBL9512026 | 0.89 | — | — | |
| Methoxymethane SCHEMBL28059599 | 0.85 | TSHR (0.39) | TSHRDNM1ALDH1A1CNR1CNR2 | |
| Di(Hydroxyethyl)Ether SCHEMBL16610460 | 0.84 | TSHR (0.61) | TSHRALDH1A1CNR1CNR2HTT | |
| Ethylene Glycol SCHEMBL5926148 | 0.83 | ALDH1A1 (0.44) | TSHRDNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL7110620 | 0.83 | ALDH1A1 (0.47) | DNM1ALDH1A1CNR1CNR2HTT | |
| SCHEMBL7110628 | 0.83 | ALDH1A1 (0.47) | DNM1ALDH1A1CNR1CNR2HTT | |
| SCHEMBL19398878 | 0.83 | — | — | |
| Butoxyethanol SCHEMBL25266385 | 0.82 | TSHR (0.65) | TSHRALDH1A1CNR1CNR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737243-A1 | LIQUID HARD SURFACE DETERGENT COMPOSITIONS CONTAINING BUILDERS | THE PROCTER & GAMBLE COMPANY (US) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995018210-A1 | LIQUID HARD SURFACE DETERGENT COMPOSITIONS CONTAINING BUILDERS | THE PROCTER & GAMBLE COMPANY (US) | 1995-07-06 | — | — | WO | disclosed |