Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 9/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 8/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 8/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.46 |
| ▸ | CFB | P00751 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2798318 | 0.76 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL7046475 | 0.75 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL7048861 | 0.74 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL8993312 | 0.69 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL24593623 | 0.67 | KDM4C (0.46) | MTNR1AMTNR1B | |
| SCHEMBL9558789 | 0.65 | CFB (0.48) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| Hydrochloric Acid SCHEMBL6076996 | 0.65 | KDM4C (0.45) | MTNR1AMTNR1B | |
| SCHEMBL23788244 | 0.65 | MTNR1A (0.57) | ADRA2AADRA2BMTNR1AMTNR1B | |
| SCHEMBL7048125 | 0.64 | TAAR1 (0.46) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL29920861 | 0.64 | ADRA2A (0.59) | ADRA2AADRA2BADRA2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580892-A | ANTIDIARRHETIC, ANTISPASTIC, ANTIEPILEPTIC AGENTS; DIURETICS | ALLERGAN | 1996-12-03 | — | — | US | disclosed |