Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 8/20 | 0.52 |
| ▸ | RXRA | P19793 | 7/20 | 0.52 |
| ▸ | RXRB | P28702 | 7/20 | 0.52 |
| ▸ | RXRG | P48443 | 5/20 | 0.52 |
| ▸ | PTGIR | P43119 | 6/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006895 | 0.90 | NR4A2 (0.54) | NR4A2RXRARXRBRXRGPTGIR | |
| SCHEMBL9006816 | 0.86 | NR4A2 (0.45) | NR4A2RXRARXRBRXRGPTGIR | |
| SCHEMBL9006854 | 0.85 | PTGIR (0.44) | NR4A2RXRARXRBRXRGPTGIR | |
| SCHEMBL8066611 | 0.84 | RXRA (0.50) | NR4A2RXRARXRBRXRGPTGIR | |
| SCHEMBL8055541 | 0.83 | FABP4 (0.58) | NR4A2RXRARXRBRXRGPTGIR | |
| SCHEMBL9006917 | 0.81 | PTGIR (0.49) | NR4A2RXRARXRBRXRGPTGIR | |
| SCHEMBL9006887 | 0.81 | PTGIR (0.49) | NR4A2RXRARXRBRXRGPTGIR | |
| SCHEMBL9006894 | 0.79 | RXRA (0.46) | NR4A2RXRARXRBRXRGPTGIR | |
| SCHEMBL9007180 | 0.79 | PTGIR (0.72) | NR4A2RXRARXRBRXRGPTGIR | |
| SCHEMBL27345477 | 0.78 | NR4A2 (0.56) | NR4A2RXRARXRBRXRGPTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736018-A1 | 4,5-DIARYLOXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |