Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 9/20 | 0.56 |
| ▸ | RXRA | P19793 | 6/20 | 0.56 |
| ▸ | RXRB | P28702 | 6/20 | 0.56 |
| ▸ | RXRG | P48443 | 5/20 | 0.56 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | RARG | P13631 | 1/20 | 0.47 |
| ▸ | PTGIR | P43119 | 4/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | C5 | P01031 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344474 | 0.83 | NR4A2 (0.48) | NR4A2RXRARXRBRXRGRARA | |
| SCHEMBL8066611 | 0.82 | RXRA (0.50) | NR4A2RXRARXRBRXRGRARA | |
| SCHEMBL27323551 | 0.81 | RXRA (0.46) | NR4A2RXRARXRBRXRGRARA | |
| SCHEMBL9006895 | 0.80 | NR4A2 (0.54) | NR4A2RXRARXRBRXRGRARA | |
| SCHEMBL8055541 | 0.79 | FABP4 (0.58) | NR4A2RXRARXRBRXRGRARA | |
| SCHEMBL9006891 | 0.78 | NR4A2 (0.52) | NR4A2RXRARXRBRXRGRARA | |
| SCHEMBL27408640 | 0.76 | PTGIR (0.46) | NR4A2RXRARXRBRXRGPTGIR | |
| SCHEMBL27337328 | 0.76 | PTGIR (0.46) | NR4A2RXRARXRBRXRGPTGIR | |
| SCHEMBL8024246 | 0.74 | HTR2C (0.56) | HTR2AHTR2CLMNACYP3A4DRD2 | |
| SCHEMBL8056373 | 0.74 | PTGIR (0.67) | NR4A2RXRARXRBRXRGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1090184-C | Heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-09-04 | — | — | CN | disclosed |
| CN-1046714-C | Diaryl oxazole derivative and its preparation method, application and pharmaceutical composition | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-11-24 | — | — | CN | disclosed |
| CN-1229795-A | Heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-09-29 | — | — | CN | disclosed |
| CN-1138328-A | Heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-12-18 | — | — | CN | disclosed |