Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 7/20 | 0.41 |
| ▸ | PTPRZ1 | P23471 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901022 | 0.85 | PTPRZ1 (0.35) | PDE2APTPRZ1PTPN1HTR2AHTR2C | |
| SCHEMBL12474365 | 0.83 | PDE2A (0.38) | PDE2APTPRZ1PTPN1HTR2AHTR2C | |
| SCHEMBL12474301 | 0.77 | PDE2A (0.41) | PDE2APTPRZ1PTPN1HTR2AHTR2C | |
| SCHEMBL900648 | 0.75 | PDE2A (0.44) | PDE2AHTR2AHTR2CHTR2B | |
| SCHEMBL10525468 | 0.74 | PDE2A (0.46) | PDE2A | |
| SCHEMBL148416 | 0.71 | KIF11 (0.53) | — | |
| SCHEMBL900649 | 0.71 | PDE2A (0.47) | PDE2AHTR2AHTR2CHTR2B | |
| SCHEMBL9404035 | 0.71 | ALDH1A1 (0.48) | PDE2AHTR2AHTR2CHTR2B | |
| SCHEMBL18247943 | 0.71 | PDE2A (0.44) | PDE2AHTR2AHTR2CHTR2B | |
| SCHEMBL31256398 | 0.71 | ALDH1A1 (0.48) | PDE2AHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |