Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 11/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900118 | 0.83 | PDE2A (0.34) | PDE2AKDM4EALDH1A1TDP1HTR2A | |
| SCHEMBL10525468 | 0.78 | PDE2A (0.46) | PDE2AKDM4EALDH1A1TDP1 | |
| SCHEMBL9404035 | 0.75 | ALDH1A1 (0.48) | PDE2AKDM4EALDH1A1TDP1HTR2A | |
| SCHEMBL18247943 | 0.75 | PDE2A (0.44) | PDE2AKDM4EALDH1A1TDP1HTR2A | |
| SCHEMBL900649 | 0.75 | PDE2A (0.47) | PDE2AHTR2AHTR2CHTR2B | |
| SCHEMBL31256398 | 0.75 | ALDH1A1 (0.48) | PDE2AKDM4EALDH1A1TDP1HTR2A | |
| SCHEMBL900701 | 0.75 | PDE2A (0.41) | PDE2AHTR2AHTR2CHTR2B | |
| SCHEMBL16958947 | 0.74 | CCR2 (0.32) | — | |
| SCHEMBL9404050 | 0.72 | PDE2A (0.45) | PDE2AKDM4EALDH1A1TDP1HTR2A | |
| SCHEMBL900737 | 0.71 | PDE2A (0.34) | PDE2AKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |