Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28204897 | 0.78 | KDM4E (0.39) | ALDH1A1BACE1KDM4ESMN1; SMN2 | |
| SCHEMBL900140 | 0.77 | TAAR1 (0.32) | — | |
| SCHEMBL12474312 | 0.77 | FFAR4 (0.35) | ALDH1A1PKMHPGDHTTL3MBTL1 | |
| SCHEMBL900114 | 0.73 | HTR2A (0.30) | — | |
| SCHEMBL900692 | 0.72 | TAAR1 (0.32) | — | |
| SCHEMBL17887570 | 0.72 | BACE1 (0.37) | ALDH1A1L3MBTL1BACE1KDM4ESMN1; SMN2 | |
| SCHEMBL900553 | 0.71 | ACHE (0.34) | ALDH1A1PKMHPGDHTTL3MBTL1 | |
| SCHEMBL900986 | 0.70 | PDE2A (0.33) | PDE2A | |
| SCHEMBL12474301 | 0.70 | PDE2A (0.41) | PDE2A | |
| SCHEMBL1958637 | 0.69 | ALDH1A1 (0.39) | ALDH1A1PKMHPGDHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |