Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900879 | 0.84 | ALOX15 (0.38) | SLC6A2SLC6A4SLC6A3ALOX15GFER | |
| SCHEMBL12474360 | 0.78 | ALOX15 (0.39) | ALOX15GFERADAM17MAPTRAB9A | |
| SCHEMBL16974786 | 0.78 | PPARG (0.54) | SLC6A2SLC6A4SLC6A3ALOX15GFER | |
| SCHEMBL18023754 | 0.76 | ALOX15 (0.42) | SLC6A2SLC6A4SLC6A3ALOX15GFER | |
| SCHEMBL16957287 | 0.76 | GPR3 (0.44) | SLC6A2SLC6A3ALOX15MAPTRAB9A | |
| SCHEMBL900747 | 0.76 | MCL1 (0.50) | MAPTRAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL17284534 | 0.76 | PPARG (0.39) | SLC6A2SLC6A4SLC6A3ALOX15GFER | |
| SCHEMBL12474304 | 0.73 | ALOX15 (0.39) | ALOX15GFERADAM17MAPTSMN1; SMN2 | |
| SCHEMBL17125208 | 0.73 | THRB (0.39) | SLC6A2SLC6A4SLC6A3ALOX15GFER | |
| SCHEMBL687956 | 0.72 | CA12 (0.48) | SLC6A4GFERMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |