Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10589205 | 0.79 | AGTR1 (0.46) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL8843482 | 0.73 | AGTR1 (0.39) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL8861079 | 0.71 | ACHE (0.46) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL10588881 | 0.67 | ACHE (0.46) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL9734324 | 0.67 | AGTR1 (0.55) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL3906504 | 0.67 | BRS3 (0.70) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL9535397 | 0.66 | AGTR1 (0.70) | AGTR1AGTR2 | |
| SCHEMBL4192326 | 0.65 | LTB4R2 (0.65) | LTB4R2 | |
| SCHEMBL10341051 | 0.65 | LTB4R2 (0.65) | LTB4R2 | |
| Hexane SCHEMBL9090054 | 0.65 | LTB4R2 (0.64) | AGTR1AGTR2LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506361-A | ACTS BOTH AS AN ANGIOTENSIN II ANTAGONIST AND A LIPIDPEROXIDATION INHIBITOR | THEUPJOHN COMPANY (US) | 1996-04-09 | — | — | US | claimed |
| WO-1992019211-A2 | IMIDAZOBENZOQUINONES AND COMPOSITION FOR PREVENTING OR TREATING HYPERTENSION OR CONGESTIVE HEART FAILURE CONTAINING THE SAME | THE UPJOHN COMPANY (US) | 1992-11-12 | — | — | WO | claimed |
| US-5506361-A | ACTS BOTH AS AN ANGIOTENSIN II ANTAGONIST AND A LIPIDPEROXIDATION INHIBITOR | THEUPJOHN COMPANY (US) | 1996-04-09 | — | — | US | disclosed |