Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.48 |
| ▸ | DRD3 | P35462 | 5/20 | 0.42 |
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030007 | 0.88 | DRD2 (0.41) | DRD2DRD3HTR1DCES1 | |
| SCHEMBL1820878 | 0.82 | DRD2 (0.53) | DRD2DRD3HTR1DBCL2L1BAD | |
| SCHEMBL3113928 | 0.79 | DRD2 (0.53) | DRD2DRD3HTR1DDRD4HTR5A | |
| SCHEMBL16812540 | 0.78 | DRD2 (0.35) | DRD2DRD3HTR1DCES1 | |
| SCHEMBL7107742 | 0.77 | DRD2 (0.36) | DRD2DRD3HTR1DCES1DRD4 | |
| SCHEMBL23336944 | 0.77 | DRD2 (0.38) | DRD2DRD3HTR1DCES1DRD4 | |
| SCHEMBL7027415 | 0.76 | DRD2 (0.37) | DRD2DRD3HTR1DCES1DRD4 | |
| SCHEMBL1506665 | 0.76 | DRD2 (0.37) | DRD2DRD3HTR1DCES1DRD4 | |
| SCHEMBL14930999 | 0.75 | DRD2 (0.48) | DRD2BCL2L1BAD | |
| SCHEMBL31673866 | 0.75 | BCL2L1 (0.44) | DRD2CES1BCL2L1BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530150-A | HAVING PHOSPHINE AND PHOSPHITE GROUPS IN SAME MOLECULE; CATALYST SELECTIVITY | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-06-25 | — | — | US | disclosed |