Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 3/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | DRD5 | P21918 | 2/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030007 | 0.85 | DRD2 (0.41) | DRD2DRD3HTR1DCES1 | |
| SCHEMBL29424782 | 0.80 | DRD1 (0.39) | CES1DRD1METAP2 | |
| SCHEMBL29924184 | 0.80 | DRD1 (0.39) | CES1DRD1METAP2 | |
| SCHEMBL665033 | 0.80 | DRD1 (0.39) | CES1DRD1METAP2 | |
| SCHEMBL9192628 | 0.78 | DRD1 (0.38) | CES1DRD1METAP2 | |
| Iodide SCHEMBL9231383 | 0.78 | DRD1 (0.38) | CES1DRD1METAP2 | |
| Iodide SCHEMBL9231386 | 0.78 | DRD1 (0.38) | CES1DRD1METAP2 | |
| SCHEMBL9007737 | 0.77 | DRD2 (0.48) | DRD2DRD3HTR1DCES1DRD1 | |
| SCHEMBL14356045 | 0.77 | DRD1 (0.39) | CES1DRD1METAP2 | |
| SCHEMBL7027415 | 0.76 | DRD2 (0.37) | DRD2DRD3HTR1DCES1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839819-B1 | Method of preparing optically active diphosphine ligands | TAKASAGO PERFUMERY CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-5922918-A | Method for making an optically active diphosphine ligand | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-07-13 | — | — | US | disclosed |
| EP-0839819-A1 | Method of preparing optically active diphosphine ligands | Takasago International Corporation (JP) | 1998-05-06 | — | — | EP | disclosed |