Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13134295 | 1.00 | SMYD2 (0.36) | SMYD2FFAR1TLR8HTTCYP3A4 | |
| SCHEMBL5030605 | 0.85 | TRPA1 (0.39) | SMYD2HTTCYP3A4SMN1; SMN2LMNA | |
| SCHEMBL4337323 | 0.85 | SMYD2 (0.35) | SMYD2HTTCYP3A4SMN1; SMN2 | |
| SCHEMBL5030604 | 0.85 | TRPA1 (0.39) | SMYD2HTTCYP3A4SMN1; SMN2LMNA | |
| SCHEMBL5026308 | 0.85 | SMYD2 (0.35) | SMYD2HTTCYP3A4SMN1; SMN2 | |
| SCHEMBL5026304 | 0.85 | SMYD2 (0.35) | SMYD2HTTCYP3A4SMN1; SMN2 | |
| SCHEMBL6445069 | 0.85 | SMYD2 (0.38) | SMYD2HTTCYP3A4SMN1; SMN2 | |
| SCHEMBL18666927 | 0.85 | SCN4A (0.39) | SMYD2HTTCYP3A4SMN1; SMN2 | |
| SCHEMBL22128202 | 0.85 | SCN4A (0.39) | SMYD2HTTCYP3A4SMN1; SMN2 | |
| SCHEMBL7051126 | 0.85 | SMYD2 (0.35) | SMYD2HTTCYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996012723-A1 | PROCESS FOR PREPARING ALKYLSILYL OR ARYLSILYL ETHERS | FMC CORPORATION (US) | 1996-05-02 | — | — | WO | disclosed |
| US-5493044-A | Process for preparing alkylsilyl or arylsilyl ethers | FMC CORPORATION (US) | 1996-02-20 | — | — | US | disclosed |