Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 3/20 | 0.54 |
| ▸ | PGK2 | P07205 | 3/20 | 0.54 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.43 |
| ▸ | ACP3 | P15309 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | PARG | Q86W56 | 1/20 | 0.37 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8740658 | 0.82 | PGK1 (0.65) | PGK1PGK2ACP3PTGS1 | |
| SCHEMBL9007814 | 0.82 | PGK1 (0.56) | PGK1PGK2PTPN5PTGS1 | |
| SCHEMBL8740626 | 0.81 | PGK1 (0.59) | PGK1PGK2PTPN5ACP3PTGS1 | |
| SCHEMBL9007805 | 0.80 | PGK1 (0.57) | PGK1PGK2PTPN5ACP3PTGS1 | |
| SCHEMBL11422056 | 0.76 | CASP1 (0.45) | GAAPTGS1XIAPSMN1; SMN2 | |
| SCHEMBL9007810 | 0.75 | PGK1 (0.59) | PGK1PGK2PTGS1 | |
| SCHEMBL11829107 | 0.75 | PTGS1 (0.71) | LMNAPOLBPTGS1CXCL8MRGPRX4 | |
| SCHEMBL9007806 | 0.74 | PGK1 (0.57) | PGK1PGK2ACP3PTGS1SMN1; SMN2 | |
| SCHEMBL9007812 | 0.74 | PGK1 (0.57) | PGK1PGK2ACP3PTGS1SMN1; SMN2 | |
| SCHEMBL11830079 | 0.73 | CASP1 (0.44) | LMNAPOLBGAAPTGS1CXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519163-A | A-HYDROXYPHOSPHONATE COMPOUNDS | MERCK & CO., INC. (US) | 1996-05-21 | — | — | US | disclosed |