Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950691 | 0.84 | DRD1 (0.33) | LMNAMEN1MAPTKMT2A | |
| SCHEMBL16953301 | 0.79 | FFAR4 (0.35) | LMNAKMT2AGAA | |
| SCHEMBL12474327 | 0.77 | APP (0.31) | — | |
| SCHEMBL16951839 | 0.75 | ALDH1A1 (0.46) | MAPTKMT2A | |
| SCHEMBL15864862 | 0.75 | ALDH1A1 (0.46) | LMNAMEN1MAPTRAB9AKMT2A | |
| SCHEMBL14000645 | 0.75 | LMNA (0.36) | LMNAMEN1MAPTRAB9AKMT2A | |
| SCHEMBL900786 | 0.75 | MEN1 (0.36) | LMNAMEN1MAPTRAB9AKMT2A | |
| SCHEMBL16960383 | 0.75 | MEN1 (0.31) | LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22081760 | 0.75 | CYP3A4 (0.48) | LMNAMEN1MAPTRAB9AKMT2A | |
| SCHEMBL16961888 | 0.75 | ALOX15 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |