Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MDM4 | O15151 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126696 | 0.82 | TP53 (0.59) | HPGDTP53MDM4HDAC3MAPK1 | |
| SCHEMBL8616070 | 0.81 | BRD4 (0.54) | HPGDPOLBKDM4EUSP2ALDH1A1 | |
| SCHEMBL527994 | 0.79 | RAB9A (0.77) | HPGDMAPK1HDAC1KDM4EALDH1A1 | |
| SCHEMBL29989592 | 0.79 | RAB9A (0.77) | HPGDMAPK1HDAC1KDM4EALDH1A1 | |
| SCHEMBL3182066 | 0.79 | ALDH1A1 (0.47) | HPGDKDM4EUSP2ALDH1A1PDE3A | |
| SCHEMBL6959171 | 0.78 | NPC1 (0.59) | HPGDTP53MDM4HDAC3MAPK1 | |
| SCHEMBL27943418 | 0.78 | MAPT (0.67) | MAPK1POLBRAB9AKMT2AMEN1 | |
| SCHEMBL16685068 | 0.78 | KMT2A (0.77) | HPGDTP53MDM4HDAC3MAPK1 | |
| SCHEMBL1110180 | 0.78 | MDM4 (0.73) | HPGDTP53MDM4HDAC3MAPK1 | |
| SCHEMBL22825227 | 0.77 | PLK1 (0.67) | TP53RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484700-A | CONTACTING PHOSPHATASE WITH SAMPLE THAT BINDS NAPHTHOL, RADIATION WITH FLUORESCENT LIGHT AND DETECTION OF NUCLEIC ACID | AISIN SEIKI KABUSHIKI KAISHA (JP) | 1996-01-16 | — | — | US | disclosed |