Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.47 |
| ▸ | PPARG | P37231 | 16/20 | 0.47 |
| ▸ | PPARD | Q03181 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879102 | 0.85 | PPARG (0.46) | PPARAPPARGPPARDKDM4EHRH3 | |
| SCHEMBL7879105 | 0.85 | PPARG (0.46) | PPARAPPARGPPARDKDM4EHRH3 | |
| SCHEMBL9521721 | 0.85 | PPARG (0.44) | PPARAPPARGPPARDKDM4EHRH3 | |
| SCHEMBL9520686 | 0.79 | PPARG (0.44) | PPARAPPARGPPARDKDM4EHRH3 | |
| SCHEMBL9721263 | 0.77 | MAPT (0.36) | PPARAPPARGPPARDKDM4E | |
| SCHEMBL9521124 | 0.74 | PPARG (0.38) | PPARAPPARGPPARDHRH3 | |
| SCHEMBL9521119 | 0.74 | PPARG (0.38) | PPARAPPARGPPARDHRH3 | |
| SCHEMBL7879307 | 0.73 | KDM4E (0.45) | PPARAPPARGPPARDKDM4EHRH3 | |
| SCHEMBL7897429 | 0.73 | PPARG (0.61) | PPARAPPARGPPARDKDM4E | |
| SCHEMBL9520129 | 0.72 | PPARG (0.40) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512689-A | TREATING A STARTING KETONE WITH A BORANE REDUCING AGENT IN THE PRESENCE OF A CHIRAL OXAZABOROLIDINE CATLAYST, PRODUCT FREE OF ENANTIMERS | PFIZER INC. (US) | 1996-04-30 | — | — | US | disclosed |