Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3035291 | 0.82 | PIN1 (0.50) | PIN1MEN1KMT2ANPC1MMP8 | |
| SCHEMBL8329718 | 0.82 | PIN1 (0.50) | PIN1MEN1KMT2ANPC1MMP8 | |
| SCHEMBL17785176 | 0.81 | MAPT (0.55) | PIN1MEN1KMT2ANPC1TSHR | |
| SCHEMBL10817048 | 0.79 | MEN1 (0.50) | PIN1MEN1KMT2ANPC1MMP8 | |
| SCHEMBL28557034 | 0.79 | PIN1 (0.47) | PIN1MEN1KMT2ANPC1MMP8 | |
| SCHEMBL9462869 | 0.78 | POLB (0.44) | KMT2ASMN1; SMN2TSHRPKMTDP1 | |
| SCHEMBL4249401 | 0.77 | PIN1 (0.45) | PIN1MEN1KMT2ANPC1MMP8 | |
| SCHEMBL3148129 | 0.77 | PIN1 (0.45) | PIN1MEN1KMT2ANPC1MMP8 | |
| SCHEMBL9547896 | 0.75 | GAA (0.44) | KMT2ANPC1SMN1; SMN2TSHRPKM | |
| SCHEMBL21247665 | 0.75 | CYP2C9 (0.45) | MEN1KMT2ASMN1; SMN2PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491152-A | Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |