SCHEMBL10817048

SCHEMBL10817048

CCOC(=O)C(F)Sc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
KMT2A Q03164 1/20 0.50
PIN1 Q13526 1/20 0.47
KDM4E B2RXH2 1/20 0.45
MMP8 P22894 2/20 0.44
PRNP P04156 1/20 0.44
MAPT P10636 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ALDH1A1 P00352 2/20 0.43
TSHR P16473 2/20 0.43
PKM P14618 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TUBB4A P04350 1/20 0.43
TUBB P07437 1/20 0.43
TUBA3C P0DPH7 1/20 0.43
TUBA1B P68363 1/20 0.43
TUBA4A P68366 1/20 0.43
TUBB4B P68371 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9788432 0.86 ALDH1A1 (0.44) MEN1NPC1KMT2AMAPTALDH1A1
SCHEMBL11748824 0.85 CA12 (0.47) MEN1NPC1KMT2APIN1KDM4E
SCHEMBL12437771 0.83 TSHR (0.48) MEN1NPC1KMT2AMMP8MAPT
SCHEMBL3035291 0.82 PIN1 (0.50) MEN1NPC1KMT2APIN1KDM4E
SCHEMBL8329718 0.82 PIN1 (0.50) MEN1NPC1KMT2APIN1KDM4E
SCHEMBL17785176 0.81 MAPT (0.55) MEN1NPC1KMT2APIN1KDM4E
SCHEMBL28557034 0.79 PIN1 (0.47) MEN1NPC1KMT2APIN1KDM4E
SCHEMBL9008098 0.79 PIN1 (0.47) MEN1NPC1KMT2APIN1KDM4E
SCHEMBL4249401 0.77 PIN1 (0.45) MEN1NPC1KMT2APIN1KDM4E
SCHEMBL3148129 0.77 PIN1 (0.45) MEN1NPC1KMT2APIN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4713469-A Fluorine-containing multifunctional ester compound DAIKIN INDUSTRIES, LTD. (JP) 1987-12-15 US disclosed