Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17785176 | 0.81 | MAPT (0.55) | PIN1MEN1NPC1KMT2AMAPT | |
| SCHEMBL8329718 | 0.80 | PIN1 (0.50) | PIN1MEN1NPC1KMT2AMAPT | |
| SCHEMBL3035291 | 0.80 | PIN1 (0.50) | PIN1MEN1NPC1KMT2AMAPT | |
| SCHEMBL5027835 | 0.79 | LMNA (0.43) | L3MBTL1PRNPALDH1A1KDM4EGAA | |
| SCHEMBL11398073 | 0.78 | MTNR1A (0.48) | PIN1MEN1NPC1KMT2AL3MBTL1 | |
| SCHEMBL13708391 | 0.78 | LMNA (0.42) | MAPTL3MBTL1PRNPALDH1A1KDM4E | |
| SCHEMBL10817048 | 0.77 | MEN1 (0.50) | PIN1MEN1NPC1KMT2AMAPT | |
| SCHEMBL9008098 | 0.77 | PIN1 (0.47) | PIN1MEN1NPC1KMT2ATDP1 | |
| SCHEMBL28557034 | 0.77 | PIN1 (0.47) | PIN1MEN1NPC1KMT2AMAPT | |
| SCHEMBL6049933 | 0.75 | MMP8 (0.53) | PIN1MEN1NPC1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582791-B2 | Process for producing optically active ester | KOWA CO., LTD. (JP) | 2009-09-01 | — | — | US | disclosed |
| US-20090118535-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ESTER | KOWA CO., LTD. (JP) | 2009-05-07 | — | — | US | disclosed |
| EP-1918271-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ESTER | Kowa Company, Ltd. (JP) | 2008-05-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118535-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ESTER | CYP8B1, HACL2, ACSL3 | PIN1 3950/4885MEN1 4507/4885NPC1 4550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.