Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31124123 | 0.78 | NPC1 (0.42) | KDM4ENPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL938005 | 0.78 | NPC1 (0.42) | KDM4ENPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7629364 | 0.78 | KDM4E (0.48) | KDM4ENPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14016487 | 0.71 | KDM4E (0.36) | KDM4ENPC1ALDH1A1LMNACYP1A2 | |
| SCHEMBL14016608 | 0.69 | KDM4E (0.38) | KDM4ENPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL5728923 | 0.67 | HTR1A (0.39) | KDM4ENPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL711331 | 0.66 | — | — | |
| SCHEMBL28458865 | 0.66 | KDM4E (0.44) | KDM4ENPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13839490 | 0.66 | RAB9A (0.39) | KDM4ENPC1ALDH1A1SMN1; SMN2LMNA | |
| Benzene SCHEMBL28297131 | 0.65 | KDM4E (0.42) | KDM4ENPC1ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532334-A | HEAT RESISTANCE | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1996-07-02 | — | — | US | disclosed |
| EP-0017422-B1 | THERMOPLASTIC POLYAMIDEIMIDE COPOLYMERS AND METHOD OF PREPARATION | TORAY INDUSTRIES, INC. (JP) | 1983-11-30 | — | — | EP | disclosed |
| US-4299945-A | HEAT POLYMERIZATION OF AN AROMATIC DIAMINO COMPOUND AND AN AROMATIC TRIBASIC CARBOXYLIC ACID | TORAY INDUSTRIES, INC. (JP) | 1981-11-10 | — | — | US | disclosed |
| EP-0017422-A1 | Thermoplastic polyamideimide copolymers and method of preparation | TORAY INDUSTRIES, INC. (JP) | 1980-10-15 | — | — | EP | disclosed |