Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | TSHR | P16473 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | STAT3 | P40763 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008391 | 0.84 | LMNA (0.83) | SMN1; SMN2LMNATSHRMEN1KMT2A | |
| SCHEMBL14028292 | 0.78 | TSHR (0.72) | LMNATSHRMEN1KMT2AUSP2 | |
| SCHEMBL9008401 | 0.78 | LMNA (0.72) | SMN1; SMN2LMNATSHRMEN1KMT2A | |
| SCHEMBL8990782 | 0.77 | LMNA (0.71) | LMNATSHRMEN1KMT2AUSP2 | |
| SCHEMBL5596807 | 0.77 | LMNA (0.59) | SMN1; SMN2LMNATSHRMEN1KMT2A | |
| SCHEMBL1581342 | 0.76 | ATM (0.67) | SMN1; SMN2LMNATSHRMEN1KMT2A | |
| SCHEMBL7435099 | 0.76 | ATM (0.76) | SMN1; SMN2MEN1KMT2APOLBATM | |
| SCHEMBL557799 | 0.74 | ATM (1.00) | SMN1; SMN2LMNATSHRKMT2APOLB | |
| Hydrochloric Acid SCHEMBL11808765 | 0.74 | ATM (0.73) | SMN1; SMN2MEN1KMT2APOLBATM | |
| SCHEMBL30230461 | 0.74 | ATM (1.00) | SMN1; SMN2LMNATSHRKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536722-A | Triazine derivatives for enhancing antitumor activity | PFIZER INC. (US) | 1996-07-16 | — | — | US | disclosed |