Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610999 | 0.80 | RAPGEF4 (0.31) | RAPGEF4KMT2A | |
| SCHEMBL12802117 | 0.80 | GAA (0.44) | RAPGEF4KMT2AKDM4EL3MBTL1 | |
| SCHEMBL1610361 | 0.77 | TAAR1 (0.31) | — | |
| SCHEMBL900740 | 0.73 | HRH3 (0.38) | RAPGEF4KMT2AKDM4E | |
| SCHEMBL598637 | 0.73 | KMT2A (0.41) | RAPGEF4KMT2AKDM4EL3MBTL1 | |
| SCHEMBL395487 | 0.71 | TAAR1 (0.40) | RAPGEF4KDM4EL3MBTL1 | |
| SCHEMBL1610418 | 0.71 | RAPGEF4 (0.35) | RAPGEF4KDM4EL3MBTL1 | |
| SCHEMBL3824444 | 0.71 | KDM4E (0.43) | RAPGEF4KMT2AKDM4EL3MBTL1 | |
| SCHEMBL395976 | 0.71 | KDM4E (0.35) | RAPGEF4KMT2AKDM4EL3MBTL1 | |
| SCHEMBL30425753 | 0.71 | SHBG (0.39) | RAPGEF4KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |