SCHEMBL598637

SCHEMBL598637

CCc1cc(C)cc(C)c1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
RAPGEF4 Q8WZA2 3/20 0.36
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
NOS2 P35228 1/20 0.35
NR3C1 P04150 2/20 0.35
NR3C2 P08235 2/20 0.35
PGR P06401 1/20 0.35
ALDH1A1 P00352 3/20 0.33
TSHR P16473 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HPGD P15428 2/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
PON1 P27169 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1262846 0.86 KMT2A (0.36) KMT2ANOS3NOS1NOS2ALDH1A1
SCHEMBL395976 0.82 KDM4E (0.35) KMT2AKDM4EL3MBTL1RAPGEF4NR3C1
SCHEMBL22432806 0.78 KMT2A (0.30) KMT2A
SCHEMBL30425753 0.77 SHBG (0.39) KDM4EL3MBTL1RAPGEF4ALDH1A1TSHR
SCHEMBL1610418 0.77 RAPGEF4 (0.35) KDM4EL3MBTL1RAPGEF4ALDH1A1MAPT
SCHEMBL395487 0.77 TAAR1 (0.40) KDM4EL3MBTL1RAPGEF4NOS3NOS1
SCHEMBL18560063 0.77 KMT2A (0.40) KMT2AKDM4EL3MBTL1RAPGEF4NOS3
SCHEMBL10317117 0.77 RAPGEF4 (0.35) KDM4EL3MBTL1RAPGEF4ALDH1A1TSHR
SCHEMBL357123 0.77 SHBG (0.39) KDM4EL3MBTL1RAPGEF4ALDH1A1TSHR
SCHEMBL3824444 0.77 KDM4E (0.43) KMT2AKDM4EL3MBTL1RAPGEF4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9568821-B2 Patterning process SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-02-14 US claimed
US-9507262-B2 Resist top-coat composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-11-29 US claimed
US-20150234278-A1 PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-08-20 US claimed
US-20150234274-A1 RESIST TOP-COAT COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-08-20 US claimed
US-6451937-B1 BY THERMALLY REACTING A FUNCTIONALIZING REAGENT AND THE HYDROCARBON IN THE PRESENCE OF A TRANSITION METAL COORDINATION CATALYST SHELL OIL COMPANY 2002-09-17 US claimed
US-20010039349-A1 Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds SHELL OIL COMPANY 2001-11-08 US claimed
US-12590219-B2 Phenol compound, conductive paste composition, method for producing conductive paste composition, conductive wire, and method for producing conductive wire SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-03-31 US disclosed
EP-4654222-A1 DEEP EUTECTIC LIQUID, BIO-ELECTRODE COMPOSITION, BIO-ELECTRODE, AND METHOD FOR PRODUCING BIO-ELECTRODE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-11-26 EP disclosed
US-20250352110-A1 BIO-ELECTRODE COMPOSITION, BIO-ELECTRODE, AND METHOD FOR PRODUCING BIO-ELECTRODE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-11-20 US disclosed
EP-4651157-A1 BIO-ELECTRODE COMPOSITION, BIO-ELECTRODE, AND METHOD FOR PRODUCING BIO-ELECTRODE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-11-19 EP disclosed
EP-4492406-B1 BIO-ELECTRODE COMPOSITION, BIO-ELECTRODE, METHOD FOR MANUFACTURING BIO-ELECTRODE SHINETSU CHEMICAL CO (JP) 2025-11-19 EP disclosed
US-20250345035-A1 ULTRASONIC COUPLING MATERIAL COMPOSITE FILM AND ULTRASONIC INSPECTION METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-11-13 US disclosed
EP-4647466-A1 ULTRASONIC COUPLING MATERIAL COMPOSITE FILM AND UNLTRASONIC INSPECTION METHOD Shin-Etsu Chemical Co., Ltd. (JP) 2025-11-12 EP disclosed
US-20040214844-A1 N4-acylcytosine nucleosides for treatment of viral infections GILEAD PHARMASSET LLC 2004-10-28 US disclosed
EP-1461041-A2 PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF ANTIVIRAL NUCLEOSIDES Pharmasset Ltd. (BB) 2004-09-29 EP disclosed
US-20030176319-A1 For therapy and prophylaxis of human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections, in human patients or other animal hosts GILEAD PHARMASSET LLC 2003-09-18 US disclosed
US-20030162992-A1 Reacting a 2,2-dialkoxyethyl halide with an appropriate carboxylate compound to obtain acetal compound; hydrolyzing the acetal to form the alpha -acyloxyacetaldehyde PHARMASSET, INC. 2003-08-28 US disclosed
WO-2003063771-A2 N4-ACYLCYTOSINE NUCLEOSIDES FOR TREATMENT OF VIRAL IINFECTIONS PHARMASSET LTD. (BB) 2003-08-07 WO disclosed
WO-2003051298-A2 PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF ANTIVIRAL NUCLEOSIDES PHARMASSET LTD. (BB) 2003-06-26 WO disclosed
WO-2003051306-A2 N4-ACYLCYTOSINE-1,3-DIOXOLANE NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS PHARMASSET LTD. (BB) 2003-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030176319-A1 For therapy and prophylaxis of human immunodeficiency virus (HIV) and hepatitis B virus (HBV) infections, in human patients or other animal hosts ENTPD5, CDA, ADA KMT2A 2577/4885KDM4E 1678/4885L3MBTL1 761/4885
US-20040214844-A1 N4-acylcytosine nucleosides for treatment of viral infections ENTPD5, DUT, PNP KMT2A 1476/4885KDM4E 1112/4885L3MBTL1 866/4885
US-20030162992-A1 Reacting a 2,2-dialkoxyethyl halide with an appropriate carboxylate compound to obtain acetal compound; hydrolyzing the acetal to form the alpha -acyloxyacetaldehyde DERA, DPYD, DHPS KMT2A 624/4885KDM4E 1415/4885L3MBTL1 2012/4885
US-20010039349-A1 Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds AHR, PAH, HRH3 KMT2A 848/4885KDM4E 2533/4885L3MBTL1 3731/4885
US-12590219-B2 Phenol compound, conductive paste composition, method for producing conductive paste composition, conductive wire, and method for producing conductive wire PYCARD, NPR1, TNNC1 KMT2A 2900/4885KDM4E 1352/4885L3MBTL1 4285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.