Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 16/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 15/20 | 0.35 |
| ▸ | RXRA | P19793 | 11/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12474308 | 0.83 | GRM2 (0.34) | KMT2AGRM2 | |
| SCHEMBL28043602 | 0.78 | GRIN2B (0.40) | GRIN2BGRIN1RXRAKCNH2KMT2A | |
| SCHEMBL900482 | 0.78 | GRIN2B (0.37) | GRIN2BGRIN1RXRAKCNH2 | |
| SCHEMBL16954400 | 0.76 | PDE4B (0.46) | KMT2AGRM2 | |
| SCHEMBL30349361 | 0.75 | GRIN2B (0.41) | GRIN2BGRIN1RXRAKCNH2KMT2A | |
| SCHEMBL29890232 | 0.75 | GRIN2B (0.38) | GRIN2BGRIN1RXRAKCNH2KMT2A | |
| SCHEMBL983555 | 0.75 | GRIN2B (0.41) | GRIN2BGRIN1RXRAKCNH2KMT2A | |
| SCHEMBL983298 | 0.75 | GRIN2B (0.38) | GRIN2BGRIN1RXRAKCNH2KMT2A | |
| SCHEMBL900869 | 0.75 | ALDH1A1 (0.45) | GRIN2BGRIN1RXRAKCNH2KMT2A | |
| SCHEMBL29525099 | 0.75 | GRIN2B (0.41) | GRIN2BGRIN1RXRAKCNH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |