Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 11/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 10/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11916155 | 0.80 | HTR1A (0.41) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL900868 | 0.78 | GRIN2B (0.35) | GRIN2BGRIN1RXRAKMT2AKCNH2 | |
| SCHEMBL30349361 | 0.78 | GRIN2B (0.41) | GRIN2BGRIN1RXRAKMT2AHTT | |
| SCHEMBL30019983 | 0.78 | RXRA (0.41) | RXRAKMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL983555 | 0.78 | GRIN2B (0.41) | GRIN2BGRIN1RXRAKMT2AALDH1A1 | |
| SCHEMBL900869 | 0.78 | ALDH1A1 (0.45) | GRIN2BGRIN1RXRAKMT2ASMN1; SMN2 | |
| SCHEMBL3819565 | 0.78 | RXRA (0.41) | RXRAKMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL900858 | 0.78 | HTT (0.36) | KMT2AHTTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL20639120 | 0.78 | CA3 (0.41) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL983298 | 0.78 | GRIN2B (0.38) | GRIN2BGRIN1RXRAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105163588-B | 4-amino-6- (4-substituted phenyl) -pyridine-2-carboxylic acid esters and 6-amino-2- (4-substituted phenyl) -pyrimidine-4-carboxylic acid esters and their use as herbicides | 美国陶氏益农公司 | 2019-01-25 | — | — | CN | disclosed |
| CN-105163588-A | 4-amino-6- (4-substituted phenyl) -pyridine-2-carboxylic acid esters and 6-amino-2- (4-substituted phenyl) -pyrimidine-4-carboxylic acid esters and their use as herbicides | DOW AGROSCIENCES LLC | 2015-12-16 | — | — | CN | disclosed |