Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | RARB | P10826 | 5/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828893 | 0.86 | ALDH1A1 (0.61) | ALDH1A1HPGDHSD17B10RARBPLK1 | |
| SCHEMBL10547849 | 0.83 | RARB (0.59) | ALDH1A1HPGDHSD17B10RARBGAA | |
| SCHEMBL11837564 | 0.81 | ALDH1A1 (0.62) | ALDH1A1HPGDHSD17B10RARBPPARA | |
| SCHEMBL24295037 | 0.81 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10RARBPPARA | |
| SCHEMBL11825855 | 0.80 | ALDH1A1 (0.62) | ALDH1A1HPGDHSD17B10RARBPPARA | |
| SCHEMBL2779653 | 0.79 | SLC7A5 (0.61) | ALDH1A1HPGDHSD17B10RARBSMN1; SMN2 | |
| SCHEMBL2779651 | 0.79 | SLC7A5 (0.61) | ALDH1A1HPGDHSD17B10RARBSMN1; SMN2 | |
| SCHEMBL6771201 | 0.79 | SLC7A5 (0.61) | ALDH1A1HPGDHSD17B10RARBSMN1; SMN2 | |
| SCHEMBL10545136 | 0.79 | RARB (0.64) | ALDH1A1HPGDHSD17B10RARBPPARA | |
| SCHEMBL10547744 | 0.78 | RARB (0.67) | ALDH1A1HPGDHSD17B10RARBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5582814-A | COMPLEX OF PARAMAGNETIC METAL AND 1-/PARA-BUTYLBENZYL/DIETHYLENETRIAMINEPENTAACETIC ACID | METASYN, INC. (US) | 1996-12-10 | — | — | US | disclosed |
| WO-1995028179-A1 | CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | METASYN, INC. (US) | 1995-10-26 | — | — | WO | disclosed |