Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.57 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.56 |
| ▸ | THRA | P10827 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 5/20 | 0.53 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RARA | P10276 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828893 | 0.95 | ALDH1A1 (0.61) | ALDH1A1S1PR1S1PR2S1PR3THRA | |
| SCHEMBL11835552 | 0.88 | PPARG (0.47) | ALDH1A1S1PR1S1PR2S1PR3THRA | |
| SCHEMBL11826787 | 0.84 | ALDH1A1 (0.47) | ALDH1A1S1PR1S1PR2S1PR3HSD17B10 | |
| SCHEMBL9008888 | 0.81 | ALDH1A1 (0.61) | ALDH1A1THRATHRBHSD17B10HPGD | |
| SCHEMBL11827938 | 0.81 | FFAR1 (0.45) | ALDH1A1S1PR1S1PR5PPARA | |
| SCHEMBL21295007 | 0.79 | ALDH1A1 (0.61) | ALDH1A1S1PR1S1PR2S1PR3THRA | |
| SCHEMBL27808300 | 0.79 | ANPEP (0.43) | ALDH1A1HSD17B10HPGDPPARA | |
| SCHEMBL9492547 | 0.79 | PPARG (0.51) | HSD17B10PPARA | |
| SCHEMBL5460504 | 0.79 | S1PR1 (0.68) | ALDH1A1S1PR1S1PR2S1PR3RARB | |
| SCHEMBL7372199 | 0.78 | PPARG (0.50) | HPGDMEN1KMT2APPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |