Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | RARB | P10826 | 2/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.50 |
| ▸ | THRA | P10827 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837564 | 0.95 | ALDH1A1 (0.62) | ALDH1A1HPGDHSD17B10RARBS1PR1 | |
| SCHEMBL11835552 | 0.89 | PPARG (0.47) | ALDH1A1HPGDHSD17B10S1PR1S1PR2 | |
| SCHEMBL9008888 | 0.86 | ALDH1A1 (0.61) | ALDH1A1HPGDHSD17B10RARBTHRA | |
| SCHEMBL11826787 | 0.86 | ALDH1A1 (0.47) | ALDH1A1HPGDHSD17B10S1PR1S1PR2 | |
| SCHEMBL11827938 | 0.82 | FFAR1 (0.45) | ALDH1A1S1PR1S1PR5SMN1; SMN2 | |
| SCHEMBL9492547 | 0.80 | PPARG (0.51) | HSD17B10 | |
| SCHEMBL27808300 | 0.80 | ANPEP (0.43) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL3433828 | 0.80 | PPARG (0.50) | HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7372199 | 0.80 | PPARG (0.50) | HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11823101 | 0.79 | PTGS2 (0.54) | RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |