Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.67 |
| ▸ | CA9 | Q16790 | 5/20 | 0.49 |
| ▸ | CA12 | O43570 | 4/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.49 |
| ▸ | SORD | Q00796 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008946 | 0.88 | ALOX5 (0.55) | ALOX5CA9CA12AKR1B1MAOB | |
| SCHEMBL9008937 | 0.87 | ALOX5 (0.67) | ALOX5CA9CA12AKR1B1MAOB | |
| SCHEMBL9008954 | 0.86 | ALOX5 (0.59) | ALOX5CA9CA12AKR1B1MAOB | |
| SCHEMBL9008978 | 0.86 | ALOX5 (0.61) | ALOX5CA9CA12AKR1B1MAOB | |
| SCHEMBL9008944 | 0.86 | ALOX5 (0.68) | ALOX5CA9CA12AKR1B1MAOB | |
| SCHEMBL15215912 | 0.84 | ALOX5 (0.58) | ALOX5CA9CA12AKR1B1MAOB | |
| SCHEMBL9008935 | 0.81 | ALOX5 (0.51) | ALOX5CA9CA12SMN1; SMN2 | |
| SCHEMBL15215309 | 0.79 | ALOX5 (0.87) | ALOX5CA9CA12AKR1B1MAOB | |
| SCHEMBL7812229 | 0.77 | ALOX5 (0.65) | ALOX5CA9CA12AKR1B1MAOB | |
| SCHEMBL9009222 | 0.76 | ALOX5 (0.61) | ALOX5CA9CA12AKR1B1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576338-A | ANTIALLERGENS, ANTIHISTAMINES, ANTIINFLAMMATORY AGENTS AND CYTOPROTECTIVE AGENTS FOR CARDIOVASCULAR DISORDERS | MERCK FROSST CANADA, INC. (CA) | 1996-11-19 | — | — | US | claimed |
| US-5576338-A | ANTIALLERGENS, ANTIHISTAMINES, ANTIINFLAMMATORY AGENTS AND CYTOPROTECTIVE AGENTS FOR CARDIOVASCULAR DISORDERS | MERCK FROSST CANADA, INC. (CA) | 1996-11-19 | — | — | US | disclosed |