Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.68 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | TPI1 | P60174 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 5/20 | 0.35 |
| ▸ | CA9 | Q16790 | 5/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | SORD | Q00796 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008937 | 0.93 | ALOX5 (0.67) | ALOX5PARP1TPI1PARP2CA12 | |
| SCHEMBL9008939 | 0.86 | ALOX5 (0.67) | ALOX5CA12CA9ALDH2AKR1B1 | |
| SCHEMBL9009222 | 0.86 | ALOX5 (0.61) | ALOX5PARP1TPI1PARP2CA12 | |
| SCHEMBL9008935 | 0.83 | ALOX5 (0.51) | ALOX5PARP1TPI1PARP2CA12 | |
| SCHEMBL9008946 | 0.81 | ALOX5 (0.55) | ALOX5CA12CA9ALDH2AKR1B1 | |
| SCHEMBL7803885 | 0.80 | ALOX5 (0.77) | ALOX5PARP1TPI1PARP2CA12 | |
| SCHEMBL15215912 | 0.79 | ALOX5 (0.58) | ALOX5CA12CA9ALDH2AKR1B1 | |
| SCHEMBL7812419 | 0.79 | ALOX5 (0.76) | ALOX5PARP1TPI1PARP2CA12 | |
| SCHEMBL9008978 | 0.76 | ALOX5 (0.61) | ALOX5CA12CA9ALDH2AKR1B1 | |
| SCHEMBL9008954 | 0.76 | ALOX5 (0.59) | ALOX5CA12CA9ALDH2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576338-A | ANTIALLERGENS, ANTIHISTAMINES, ANTIINFLAMMATORY AGENTS AND CYTOPROTECTIVE AGENTS FOR CARDIOVASCULAR DISORDERS | MERCK FROSST CANADA, INC. (CA) | 1996-11-19 | — | — | US | claimed |
| US-5576338-A | ANTIALLERGENS, ANTIHISTAMINES, ANTIINFLAMMATORY AGENTS AND CYTOPROTECTIVE AGENTS FOR CARDIOVASCULAR DISORDERS | MERCK FROSST CANADA, INC. (CA) | 1996-11-19 | — | — | US | disclosed |