SCHEMBL9008980

SCHEMBL9008980

O=C(O)c1ccc(C(c2ccccc2)(c2cccc(C(=O)O)c2)C(F)(F)F)cc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 3/20 0.58
KMO O15229 1/20 0.47
RXRA P19793 2/20 0.46
RXRB P28702 2/20 0.46
CES2 O00748 2/20 0.46
KCNK3 O14649 1/20 0.46
DAO P14920 1/20 0.45
TSHR P16473 1/20 0.45
NAPRT Q6XQN6 1/20 0.45
KIF11 P52732 1/20 0.44
PTPN1 P18031 1/20 0.44
LMNA P02545 1/20 0.44
CES1 P23141 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
AKR1C3 P42330 1/20 0.43
AKR1C2 P52895 1/20 0.43
EPHX2 P34913 1/20 0.43
NR4A2 P43354 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9009108 0.95 SRD5A2 (0.54) SRD5A2KMORXRARXRBCES2
SCHEMBL765966 0.90 SRD5A2 (0.55) SRD5A2RXRARXRBCES2DAO
SCHEMBL10558699 0.90 SRD5A2 (0.55) SRD5A2RXRARXRBCES2DAO
SCHEMBL11358313 0.84 SRD5A2 (0.61) SRD5A2RXRARXRBCES2TSHR
SCHEMBL4611978 0.81 SRD5A2 (0.63) SRD5A2RXRARXRBCES2KCNK3
SCHEMBL9719919 0.81 SRD5A2 (0.57) SRD5A2TSHRMEN1KMT2AAKR1C3
SCHEMBL16429290 0.79 SRD5A2 (0.59) SRD5A2RXRARXRBCES2KCNK3
SCHEMBL545227 0.78 SRD5A2 (0.57) SRD5A2KMORXRARXRBCES2
SCHEMBL29420736 0.78 SRD5A2 (0.57) SRD5A2KMORXRARXRBCES2
SCHEMBL5115473 0.78 SRD5A2 (0.62) SRD5A2KMORXRARXRBCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5534614-A Method for the preparation of amide oligomers and polybenzazole polymers therefrom THE DOW CHEMICAL COMPANY (US) 1996-07-09 US disclosed
US-5322916-A Method for the preparation of amide oligomers and polybenzazole polymers therefrom THE DOW CHEMICAL COMPANY (US) 1994-06-21 US disclosed