SCHEMBL9009037

SCHEMBL9009037

CCCCCCC(C)Oc1cc[c]cc1C#N

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
HPGD P15428 1/20 0.35
MAPT P10636 1/20 0.32
AR P10275 1/20 0.32
KDM4E B2RXH2 1/20 0.30
KMT2A Q03164 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
TSHR P16473 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9009041 1.00 ALDH1A1 (0.36) ALDH1A1HPGDMAPTARKDM4E
SCHEMBL7692079 0.82 ALDH1A1 (0.44) ALDH1A1HPGDARKDM4EKMT2A
SCHEMBL7692082 0.82 ALDH1A1 (0.44) ALDH1A1HPGDARKDM4EKMT2A
SCHEMBL7693706 0.77 ALDH1A1 (0.45) ALDH1A1HPGDMAPTARKMT2A
SCHEMBL7693709 0.77 ALDH1A1 (0.45) ALDH1A1HPGDMAPTARKMT2A
SCHEMBL7698544 0.77 ALDH1A1 (0.42) ALDH1A1HPGDMAPTAR
SCHEMBL7698548 0.77 ALDH1A1 (0.42) ALDH1A1HPGDMAPTAR
SCHEMBL933149 0.76 XDH (0.40)
SCHEMBL8926312 0.75 GAA (0.38) ALDH1A1HPGDMAPTKMT2AL3MBTL1
SCHEMBL8926315 0.75 GAA (0.38) ALDH1A1HPGDMAPTKMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0738312-A1 LIQUID CRYSTAL COMPOUNDS, MIXTURES AND DEVICES THE SECRETARY OF STATE FOR DEFENCE (GB) 1996-10-23 EP disclosed
WO-1995018848-A1 LIQUID CRYSTAL COMPOUNDS, MIXTURES AND DEVICES THE SECRETARY OF STATE FOR DEFENCE (GB) 1995-07-13 WO disclosed