Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 7/20 | 0.40 |
| ▸ | VEGFA | P15692 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2105498 | 0.82 | SLC6A9 (0.35) | — | |
| SCHEMBL1420151 | 0.81 | KCNN4 (0.34) | — | |
| SCHEMBL230031 | 0.79 | ALDH1A1 (0.48) | — | |
| SCHEMBL676940 | 0.78 | ALDH1A1 (0.35) | — | |
| SCHEMBL27712841 | 0.77 | XDH (0.44) | XDH | |
| SCHEMBL9009037 | 0.76 | ALDH1A1 (0.36) | — | |
| SCHEMBL9009041 | 0.76 | ALDH1A1 (0.36) | — | |
| SCHEMBL1871847 | 0.75 | GAA (0.50) | XDH | |
| SCHEMBL1230716 | 0.75 | IRAK4 (0.32) | — | |
| SCHEMBL29530994 | 0.75 | GAA (0.50) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11465977-B2 | Process for the preparation of sphingosine-1-phosphate receptor agonist | Química Sintética, S.A. (ES) | 2022-10-11 | — | — | US | claimed |
| US-20220033365-A1 | PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST | Química Sintética, S.A. (ES) | 2022-02-03 | — | — | US | claimed |
| EP-3856738-A1 | PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST | Química Sintética, S.A. (ES) | 2021-08-04 | — | — | EP | claimed |
| CN-109071506-B | Substituted 2- (hetero) arylimidazolyl carboxamides as pest control agents | 拜耳作物科学股份公司 | 2021-03-02 | — | — | CN | claimed |
| WO-2020064818-A1 | PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST | Química Sintética, S.A. (ES) | 2020-04-02 | — | — | WO | claimed |
| US-10544124-B2 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-28 | — | — | US | claimed |
| US-20190047982-A1 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-02-14 | — | — | US | claimed |
| EP-3414236-A1 | SUBSTITUIERTED 2-(HET)ARYL-IMIDAZOLYL-CARBOXYAMIDES AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-12-19 | — | — | EP | claimed |
| US-9090593-B2 | Bicyclic compounds as Pim inhibitors | AMGEN INC. (US) | 2015-07-28 | — | — | US | claimed |
| EP-2796456-A1 | Bicyclic compounds as Pim inhibitors | Amgen Inc. (US) | 2014-10-29 | — | — | EP | claimed |
| EP-1742907-A4 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2008-01-02 | — | — | EP | claimed |
| US-20070219192-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-09-20 | — | — | US | claimed |
| US-20070197640-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2007-08-23 | — | — | US | claimed |
| US-20070197481-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-08-23 | — | — | US | claimed |
| WO-2007056056-A2 | MITOTIC KINESIN INHIBITORS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | claimed |
| WO-2007056143-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | claimed |
| EP-1742907-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2007-01-17 | — | — | EP | claimed |
| US-20060247289-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2006-11-02 | — | — | US | claimed |
| US-20060094708-A1 | to treat cellular proliferative diseases, hyperplasias, solid tumor, cardiac hypertrophy, immune disorders and inflammation; modulators of one or more mitotic kinesins; N-(2-(2-dimethylamino-acetylamino)-1-{4-[8-(1-hydroxy-ethyl)-imidazo[1,2-a]pyridin-2-yl]-benzyl}-ethyl)-3-chloro-4-isopropoxy-benzamide | CYTOKINETICS, INCORPORATED | 2006-05-04 | — | — | US | claimed |
| WO-2005107762-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2005-11-17 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190047982-A1 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | DDT, CYP4X1, CYP4Z1 | XDH 584/4885VEGFA 3379/4885CYP11B1 1311/4885 |
| US-20070197640-A1 | Certain chemical entities, compositions, and methods | KIF5B, KIF2C, PLK1 | XDH 3591/4885VEGFA 4637/4885CYP11B1 2868/4885 |
| US-20060094708-A1 | to treat cellular proliferative diseases, hyperplasias, solid tumor, cardiac hypertrophy, immune disorders and inflammation; modulators of one or more mitotic kinesins; N-(2-(2-dimethylamino-acetylamino)-1-{4-[8-(1-hydroxy-ethyl)-imidazo[1,2-a]pyridin-2-yl]-benzyl}-ethyl)-3-chloro-4-isopropoxy-benzamide | KIF5B, KIF18A, KIF2C | XDH 4868/4885VEGFA 3948/4885CYP11B1 3275/4885 |
| US-20070219192-A1 | Certain chemical entities, compositions, and methods | KIF5B, KIF2C, PLK1 | XDH 3591/4885VEGFA 4637/4885CYP11B1 2868/4885 |
| US-20060247289-A1 | Certain chemical entities, compositions, and methods | KIF5B, KIF2C, PLK1 | XDH 3591/4885VEGFA 4637/4885CYP11B1 2868/4885 |
| US-20220033365-A1 | PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST | S1PR1, S1PR4, S1PR3 | XDH 4042/4885VEGFA 2128/4885CYP11B1 1525/4885 |
| US-11465977-B2 | Process for the preparation of sphingosine-1-phosphate receptor agonist | S1PR1, S1PR4, S1PR3 | XDH 4042/4885VEGFA 2128/4885CYP11B1 1525/4885 |
| US-10544124-B2 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | DDT, CYP4X1, CYP4Z1 | XDH 584/4885VEGFA 3379/4885CYP11B1 1311/4885 |
| US-20070197481-A1 | Certain chemical entities, compositions, and methods | KIF5B, KIF2C, PLK1 | XDH 3591/4885VEGFA 4637/4885CYP11B1 2868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.