Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | BCHE | P06276 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9009060 | 0.86 | MAPK1 (0.70) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL9009230 | 0.82 | LMNA (0.68) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL10602592 | 0.81 | MAPK1 (0.64) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL29406737 | 0.81 | MEN1 (1.00) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL388483 | 0.81 | MEN1 (1.00) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL9009195 | 0.79 | TDP1 (0.76) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL22778911 | 0.78 | MAPK1 (0.65) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL28497697 | 0.77 | MAPK1 (0.65) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL30963493 | 0.77 | MAPK1 (0.65) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL11143818 | 0.77 | MEN1 (0.90) | MAPK1MEN1KMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565402-A | RECORDING LAYER CONTAINING BLACK-FORMING FLUORAN DERIVATIVE AS BASIC DYE, PHENOTHIAZINE DERIVATIVE, DIPHENYL SULFONE DERIVATIVE COLOR ACCEPTOR | NEW OJI PAPER CO., LTD. (JP) | 1996-10-15 | — | — | US | disclosed |
| US-4567019-A | RAPID, REVERSIBLE THERMOCHROMISM | GRAPHIC CONTROLS CORPORATION (US) | 1986-01-28 | — | — | US | disclosed |