SCHEMBL9009151

SCHEMBL9009151

CCCC[Si](CCCC)(c1ccc(O)c(N)c1)c1ccc(O)c(N)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.68
ESR1 P03372 4/20 0.53
ESR2 Q92731 3/20 0.53
ALDH1A1 P00352 8/20 0.41
ALOX15 P16050 4/20 0.41
HSD17B10 Q99714 4/20 0.41
GAA P10253 7/20 0.41
HPGD P15428 3/20 0.41
PKM P14618 2/20 0.41
USP2 O75604 2/20 0.41
MAPT P10636 4/20 0.38
ALOX12 P18054 3/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
RECQL P46063 2/20 0.38
HTT P42858 2/20 0.38
HIF1A Q16665 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
MAPK1 P28482 1/20 0.37
KDM4E B2RXH2 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13086248 0.71 ALDH1A1 (0.52) ARESR1ESR2ALDH1A1ALOX15
SCHEMBL6852410 0.71 ALDH1A1 (0.52) ARESR1ESR2ALDH1A1ALOX15
SCHEMBL76664 0.69 SKP2 (0.59) ESR1ALDH1A1ALOX15HSD17B10GAA
SCHEMBL1256802 0.68 KAT8 (0.57) ESR1ALDH1A1ALOX15HSD17B10HIF1A
SCHEMBL13303309 0.68 GAA (0.56) ALDH1A1ALOX15HSD17B10GAAHPGD
SCHEMBL6853210 0.68 ALDH1A1 (0.44) ARESR1ESR2ALDH1A1ALOX15
SCHEMBL8407505 0.67 AR (0.56) ARESR1ESR2ALDH1A1HPGD
SCHEMBL8937894 0.67 KAT8 (0.59) ESR1ALDH1A1ALOX15HSD17B10HIF1A
Hydrochloric Acid SCHEMBL11838688 0.67 MAPT (0.59) ALDH1A1ALOX15HSD17B10GAAMAPT
SCHEMBL9001576 0.67 KAT8 (0.59) ESR1ALDH1A1ALOX15HSD17B10HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5534614-A Method for the preparation of amide oligomers and polybenzazole polymers therefrom THE DOW CHEMICAL COMPANY (US) 1996-07-09 US disclosed
US-5322916-A Method for the preparation of amide oligomers and polybenzazole polymers therefrom THE DOW CHEMICAL COMPANY (US) 1994-06-21 US disclosed
US-5011753-A Polyamides Containing Hexafluoroisopropylidene Groups Which May Be Cured To Form Polybenzoxazoles HOECHST CELANESE CORPORATION (US) 1991-04-30 US disclosed
US-4939215-A CHEMICAL AND RADIATION RESISTANCE; AIRCRAFT, ELECTRONICS HOECHST CELANESE CORPORATION (US) 1990-07-03 US disclosed
US-4845183-A MOLDING MATERIALS; FOR DIELECTRICS OR COATING SOLUTIONS; TOUGHNESS, FLEXIBILITY, TRANSPARENT HOECHST CELANESE CORPORATION (US) 1989-07-04 US disclosed
EP-0317942-A2 Heat resistant polyamides and polybenzoxazoles from bis-[(aminohydroxyphenyl hexafluoro-isopropyl] diphenyl ethers HOECHST CELANESE CORPORATION (US) 1989-05-31 EP disclosed