Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5555274 | 0.84 | LMNA (0.34) | LMNATSHRMAPK1CA1CA2 | |
| SCHEMBL621840 | 0.82 | LMNA (0.49) | LMNA | |
| Iosimide SCHEMBL898150 | 0.80 | CA2 (0.33) | CA1CA2 | |
| Iosimide SCHEMBL8845588 | 0.80 | CA2 (0.33) | CA1CA2 | |
| SCHEMBL7590959 | 0.79 | LMNA (0.34) | LMNA | |
| SCHEMBL7607980 | 0.78 | LMNA (0.47) | LMNA | |
| SCHEMBL9194186 | 0.78 | LMNA (0.47) | LMNATSHRMAPK1 | |
| SCHEMBL9191001 | 0.77 | LMNA (0.44) | LMNA | |
| SCHEMBL10454950 | 0.76 | LMNA (0.53) | LMNA | |
| SCHEMBL11387512 | 0.75 | TSHR (0.47) | LMNATSHRMAPK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571593-B1 | NEW NON IONIC IODIZED AGENTS FOR X-RAY CONTRASTING, METHOD FOR PREPARING THEM AND GALENICAL COMPOSITIONS CONTAINING THEM | INVEST JUSTESA IMAGEN S A CENT (ES) | 1996-10-30 | — | — | EP | disclosed |