Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 6/20 | 0.42 |
| ▸ | GABRD | O14764 | 6/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.42 |
| ▸ | GABRE | P78334 | 6/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31267268 | 1.00 | MEN1 (0.47) | MEN1KMT2ATDP1CYP3A4ALDH1A1 | |
| SCHEMBL10125299 | 1.00 | MEN1 (0.47) | MEN1KMT2ATDP1CYP3A4ALDH1A1 | |
| SCHEMBL9009430 | 1.00 | MEN1 (0.47) | MEN1KMT2ATDP1CYP3A4ALDH1A1 | |
| SCHEMBL10125292 | 0.86 | GABRP (0.43) | MEN1KMT2ACYP3A4GABRPGABRD | |
| SCHEMBL8503805 | 0.80 | ABCB1 (0.49) | MEN1KMT2ATDP1LMNA | |
| SCHEMBL8995585 | 0.80 | GRIN2D (0.39) | MEN1KMT2ACYP3A4GABRPGABRD | |
| SCHEMBL13410550 | 0.79 | CYP3A4 (0.46) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10054936 | 0.79 | GRIN2D (0.38) | MEN1KMT2ACYP3A4GABRPGABRD | |
| SCHEMBL20110153 | 0.79 | GRIN2D (0.38) | MEN1KMT2ACYP3A4GABRPGABRD | |
| SCHEMBL10125405 | 0.79 | GRIN2D (0.38) | MEN1KMT2ACYP3A4GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585368-A | SKIN DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |