Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14619118 | 0.85 | CYP3A4 (0.35) | CYP3A4CDC25ACDC25BMEN1KMT2A | |
| SCHEMBL13410438 | 0.85 | CYP3A4 (0.35) | CYP3A4CDC25ACDC25BMEN1KMT2A | |
| SCHEMBL31267268 | 0.79 | MEN1 (0.47) | CYP3A4GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL10125299 | 0.79 | MEN1 (0.47) | CYP3A4GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL9009430 | 0.79 | MEN1 (0.47) | CYP3A4GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL9009451 | 0.79 | MEN1 (0.47) | CYP3A4GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL13853984 | 0.78 | CDC25A (0.50) | GRIN1GRIN2BCDC25ACDC25BMEN1 | |
| SCHEMBL13392642 | 0.75 | MEN1 (0.37) | CYP3A4CDC25ACDC25BCHRM2MEN1 | |
| SCHEMBL13392666 | 0.75 | MEN1 (0.37) | CYP3A4CDC25ACDC25BCHRM2MEN1 | |
| SCHEMBL13392661 | 0.75 | CDC25A (0.50) | CDC25ACDC25BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093675-A1 | NOVEL METHOD | BIOXELL S.P.A. (IT) | 2010-04-15 | — | — | US | disclosed |
| US-20100069339-A1 | NOVEL METHOD OF TREATMENT OF MALE SUB-FERTILITY | BIOXELL S.P.A. (IT) | 2010-03-18 | — | — | US | disclosed |
| US-20100009949-A1 | NOVEL METHOD | BIOXELL S.P.A. (IT) | 2010-01-14 | — | — | US | disclosed |
| US-20090137828-A1 | Synthesis of 1A-Fluoro-25-Hydroxy-16-23E-Diene-26,27-Bishomo-20-Epi-Cholecalciferol | BIOXELL S.P.A. (IT) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069339-A1 | NOVEL METHOD OF TREATMENT OF MALE SUB-FERTILITY | CYP27B1, CYP2R1, SHBG | CYP3A4 1018/4885GRIN1 4237/4885GRIN2B 4514/4885 |
| US-20090137828-A1 | Synthesis of 1A-Fluoro-25-Hydroxy-16-23E-Diene-26,27-Bishomo-20-Epi-Cholecalciferol | CYP24A1, CYP2R1, CYP27B1 | CYP3A4 172/4885GRIN1 4430/4885GRIN2B 4684/4885 |
| US-20100009949-A1 | NOVEL METHOD | CYP24A1, CYP2R1, CYP27B1 | CYP3A4 1785/4885GRIN1 4077/4885GRIN2B 4392/4885 |
| US-20100093675-A1 | NOVEL METHOD | GC, VDR, CYP24A1 | CYP3A4 4138/4885GRIN1 3728/4885GRIN2B 4274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.