Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 6/20 | 0.42 |
| ▸ | GABRD | O14764 | 6/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.42 |
| ▸ | GABRE | P78334 | 6/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9009451 | 1.00 | MEN1 (0.47) | MEN1KMT2ATDP1CYP3A4ALDH1A1 | |
| SCHEMBL31267268 | 1.00 | MEN1 (0.47) | MEN1KMT2ATDP1CYP3A4ALDH1A1 | |
| SCHEMBL9009430 | 1.00 | MEN1 (0.47) | MEN1KMT2ATDP1CYP3A4ALDH1A1 | |
| SCHEMBL10125292 | 0.86 | GABRP (0.43) | MEN1KMT2ACYP3A4GABRPGABRD | |
| SCHEMBL8503805 | 0.80 | ABCB1 (0.49) | MEN1KMT2ATDP1LMNA | |
| SCHEMBL8995585 | 0.80 | GRIN2D (0.39) | MEN1KMT2ACYP3A4GABRPGABRD | |
| SCHEMBL13410550 | 0.79 | CYP3A4 (0.46) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10054936 | 0.79 | GRIN2D (0.38) | MEN1KMT2ACYP3A4GABRPGABRD | |
| SCHEMBL20110153 | 0.79 | GRIN2D (0.38) | MEN1KMT2ACYP3A4GABRPGABRD | |
| SCHEMBL10125405 | 0.79 | GRIN2D (0.38) | MEN1KMT2ACYP3A4GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240327320-A1 | NOVEL ROUTES OF CHEMICAL SYNTHESIS OF 20S(OH)D3, 20S,25(OH)2D3, 20S,23S(OH)2D3, AND 20S,23R(OH)2D3 AND THEIR MODIFICATION OF THE IMMUNE ACTIVITY OF PBMCS | UNIVERSITY OF WARSAW (PL) | 2024-10-03 | — | — | US | disclosed |
| EP-2419403-B1 | VITAMIN D RECEPTOR AGONISTS AND USES THEREOF | VIDASYM INC (US) | 2016-09-07 | — | — | EP | disclosed |
| EP-2419403-B1 | VITAMIN D RECEPTOR AGONISTS AND USES THEREOF | VIDASYM INC (US) | 2016-09-07 | — | — | EP | disclosed |
| US-20120115824-A1 | Vitamin D Receptor Agonists and Uses Thereof | VIDASYM, LLC (US) | 2012-05-10 | — | — | US | disclosed |
| US-20120115824-A1 | Vitamin D Receptor Agonists and Uses Thereof | VIDASYM, LLC (US) | 2012-05-10 | — | — | US | disclosed |
| WO-2010120698-A1 | VITAMIN D RECEPTOR AGONISTS AND USES THEREOF | VIDASYM, LLC (US) | 2010-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327320-A1 | NOVEL ROUTES OF CHEMICAL SYNTHESIS OF 20S(OH)D3, 20S,25(OH)2D3, 20S,23S(OH)2D3, AND 20S,23R(OH)2D3 AND THEIR MODIFICATION OF THE IMMUNE ACTIVITY OF PBMCS | CYP2R1, VDR, CYP24A1 | MEN1 3873/4885KMT2A 3785/4885TDP1 3541/4885 |
| US-20120115824-A1 | Vitamin D Receptor Agonists and Uses Thereof | VDR, CYP2R1, CYP24A1 | MEN1 2539/4885KMT2A 4484/4885TDP1 2394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.