Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12868106 | 0.84 | AR (0.41) | ARKCNK3KCNK9P2RX3P2RX2 | |
| SCHEMBL807278 | 0.80 | KCNK3 (0.52) | ARKCNK3KCNK9P2RX3P2RX2 | |
| SCHEMBL26505533 | 0.79 | AR (0.40) | ARKCNK3KCNK9P2RX3P2RX2 | |
| SCHEMBL9009489 | 0.78 | GAA (0.34) | KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL8528296 | 0.76 | RECQL (0.40) | ARKCNK3KCNK9P2RX3P2RX2 | |
| SCHEMBL13019851 | 0.74 | CYP3A4 (0.43) | ARKCNK3KCNK9P2RX3P2RX2 | |
| Lithium Ion SCHEMBL6239438 | 0.72 | — | — | |
| SCHEMBL27415708 | 0.72 | GABRA1 (0.40) | ARKCNK3KCNK9P2RX3P2RX2 | |
| SCHEMBL706600 | 0.70 | TSHR (0.35) | KMT2ACYP1A2MEN1CYP2C19LMNA | |
| SCHEMBL2737257 | 0.70 | NISCH (0.46) | ARP2RX3P2RX2GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484953-A | CHEMICAL INTERMEDIATES FOR BENZIMIDAZOLES FOR INSECTICIDES OR NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-16 | — | — | US | disclosed |