SCHEMBL4887210

SCHEMBL4887210

C=CC(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 5/20 0.42
TSHR P16473 4/20 0.42
HTT P42858 1/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KCNN4 O15554 2/20 0.38
HSP90AA1 P07900 1/20 0.36
AKT1 P31749 1/20 0.36
ALOX15 P16050 1/20 0.36
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
CYP3A4 P08684 2/20 0.34
PTPN1 P18031 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28803531 0.89 CYP2C9 (0.48) KDM4EALDH1A1TSHRCYP2C9CYP3A4
SCHEMBL11621380 0.89 ESR1 (0.52) KDM4EALDH1A1TSHRESR1ESR2
SCHEMBL28465159 0.87 ALDH1A1 (0.56) KDM4EALDH1A1TSHRCYP3A4
SCHEMBL13452327 0.87 KDM4E (0.41) KDM4EALDH1A1TSHRHTTCYP1A2
SCHEMBL11621804 0.87 KMT2A (0.43) KDM4ETSHRHTTCYP1A2CYP3A4
SCHEMBL29140377 0.87 KDM4E (0.44) KDM4EALDH1A1TSHRHTTESR1
SCHEMBL11623660 0.87 KCNN4 (0.47) KDM4EALDH1A1TSHRHTTCYP2C9
SCHEMBL11619282 0.87 KDM4E (0.41) KDM4EALDH1A1TSHRHTTCYP1A2
SCHEMBL3906029 0.83 KDM4E (0.57) KDM4EALDH1A1TSHRHTTCYP1A2
SCHEMBL3906030 0.83 KDM4E (0.57) KDM4EALDH1A1TSHRHTTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362338-A Method for preparing 3, 3-diaryl allyl substituted organic phosphonate compound 湖南理工学院 2024-01-09 CN claimed
CN-111848441-B N-substituted benzoyl hydrazone compound and preparation method and application thereof 山东中新科农生物科技有限公司 2023-02-17 CN claimed
CN-111848441-A N-substituted benzoyl hydrazone compound and preparation method and application thereof 朱翠萍 2020-10-30 CN claimed
US-10112896-B2 Method for synthesizing dissymmetric sulfoether SOOCHOW UNIVERSITY (CN) 2018-10-30 US claimed
US-20180201576-A1 METHOD FOR SYNTHESIZING DISSYMMETRIC SULFOETHER SOOCHOW UNIVERSITY (CN) 2018-07-19 US claimed
US-8530693-B1 Liquid cyanate esters THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2013-09-10 US claimed
US-4111915-A LITHIUM ALKENOXIDES IN PREPARATION OF FUNCTIONAL LIQUID CONJUGATED DIENE POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1978-09-05 US claimed
US-20250257095-A1 METHOD FOR VISIBLE LIGHT-MEDIATED CHEMICAL MODIFICATION OF POLYPEPTIDE AND PROTEIN BASED ON CYSTEINE SHANGHAI JIAO TONG UNIVERSITY (CN) 2025-08-14 US disclosed
EP-4545545-A1 VISIBLE LIGHT-MEDIATED CYSTEINE-BASED POLYPEPTIDE AND PROTEIN CHEMICAL MODIFICATION METHOD Shanghai Jiao Tong University (CN) 2025-04-30 EP disclosed
CN-118507421-A Laminate containing novolac resin as release layer 日产化学株式会社 2024-08-16 CN disclosed
CN-111316401-B Laminate containing novolac resin as release layer 日产化学株式会社 2024-08-02 CN disclosed
CN-114805148-B Synthesis method of beta-carbonyl sulfide compound 陇东学院 2024-04-23 CN disclosed
WO-2024007714-A1 VISIBLE LIGHT-MEDIATED CYSTEINE-BASED POLYPEPTIDE AND PROTEIN CHEMICAL MODIFICATION METHOD 上海交通大学 2024-01-11 WO disclosed
EP-0154806-A2 Substituted oxiranes BAYER AG (DE) 1985-09-18 EP disclosed
US-4206140-A INSECTICIDES, ANTHELMINTICS ROUSSEL UCLAF (FR) 1980-06-03 US disclosed
US-4111915-A LITHIUM ALKENOXIDES IN PREPARATION OF FUNCTIONAL LIQUID CONJUGATED DIENE POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1978-09-05 US disclosed
US-4101574-A Cyclopropanecarboxylic acid chlorides ROUSSEL UCLAF (FR) 1978-07-18 US disclosed
US-4094908-A Alpha-substituted benzhydrol derivatives RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1978-06-13 US disclosed
US-4039589-A LIVER MICROSOMAL ENZYMES RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1977-08-02 US disclosed
US-3997586-A Cyclopropanecarboxylic acids and esters ROUSSEL-UCLAF (FR) 1976-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10112896-B2 Method for synthesizing dissymmetric sulfoether STS, TST, SCLY KDM4E 2673/4885ALDH1A1 842/4885TSHR 1975/4885
US-20180201576-A1 METHOD FOR SYNTHESIZING DISSYMMETRIC SULFOETHER STS, TST, SCLY KDM4E 2673/4885ALDH1A1 842/4885TSHR 1975/4885
US-20250257095-A1 METHOD FOR VISIBLE LIGHT-MEDIATED CHEMICAL MODIFICATION OF POLYPEPTIDE AND PROTEIN BASED ON CYSTEINE PTMS, CTH, CISD1 KDM4E 4642/4885ALDH1A1 2160/4885TSHR 2750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.