SCHEMBL900990

SCHEMBL900990

C[CH]Cc1c(C)ccc(C)c1C

nearest known ligand 0.30

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30
TSHR P16473 1/20 0.30
TDP2 O95551 1/20 0.30
NSD2 O96028 1/20 0.30
HSP90AA1 P07900 1/20 0.30
PAX8 Q06710 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1609873 0.78
SCHEMBL3047788 0.78 ALDH1A1 (0.34) TSHR
SCHEMBL1609914 0.75
SCHEMBL900695 0.73 SMN1; SMN2 (0.30)
SCHEMBL5250986 0.73 NQO1 (0.38) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL3456090 0.70 NOS2 (0.43) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL358550 0.69 GABRA1 (0.36) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL10752183 0.69 CYP1A2 (0.32) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL395903 0.69 POLB (0.35) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL21865896 0.69 PON1 (0.36) CYP1A2CYP2A6TSHRTDP2NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2621922-A1 A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS BASF SE (DE) 2013-08-07 EP disclosed
WO-2012041858-A1 A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS BASF SE (DE) 2012-04-05 WO disclosed