Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750244 | 0.84 | NPC1 (0.37) | NPC1RAB9AKMT2ACYP3A4MEN1 | |
| SCHEMBL6905535 | 0.78 | KMT2A (0.38) | PTGS2KMT2ACA12CA1CA2 | |
| SCHEMBL31462333 | 0.74 | PTGS2 (0.41) | PTGS2KMT2ACYP3A4MEN1TSHR | |
| SCHEMBL2860505 | 0.73 | NPC1 (0.45) | NPC1RAB9ACYP3A4TSHRPIK3CA | |
| SCHEMBL3628525 | 0.71 | MEN1 (0.54) | PTGS2NPC1RAB9AKMT2ACYP3A4 | |
| SCHEMBL11409408 | 0.71 | KMT2A (0.42) | PTGS2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8763662 | 0.70 | TLR8 (0.42) | PTGS2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL9515893 | 0.69 | HPGD (0.39) | PTGS2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL28126730 | 0.69 | MEN1 (0.52) | PTGS2NPC1RAB9AKMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL16445779 | 0.69 | MEN1 (0.52) | PTGS2NPC1RAB9AKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534036-A | Keratinous fiber dyeing methods and compositions which contain sulfated methaphenylenediamine couplers in combination with oxidation dye precursors | L'OREAL (FR) | 1996-07-09 | — | — | US | disclosed |