Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | APLNR | P35414 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21102991 | 0.85 | L3MBTL1 (0.43) | HPGDMAPTMEN1LMNATP53 | |
| SCHEMBL24548502 | 0.85 | LMNA (0.42) | HPGDMEN1LMNATP53KMT2A | |
| SCHEMBL14873186 | 0.82 | AR (0.34) | HPGDMAPTMEN1LMNATP53 | |
| SCHEMBL14734011 | 0.81 | HSD17B10 (0.42) | HPGDMAPTMEN1LMNATP53 | |
| SCHEMBL16279674 | 0.78 | PTGS2 (0.39) | HPGDMAPTTP53KMT2APTGS2 | |
| SCHEMBL14733971 | 0.78 | PKM (0.44) | HPGDMAPTMEN1LMNATP53 | |
| SCHEMBL20080184 | 0.77 | MAPT (0.32) | HPGDMAPTMEN1LMNATP53 | |
| SCHEMBL21939453 | 0.76 | CSNK2A1 (0.44) | MEN1TP53KMT2ANPC1RAB9A | |
| SCHEMBL10871739 | 0.76 | PTGS2 (0.43) | MAPTMEN1TP53KMT2AHSD17B10 | |
| SCHEMBL1369742 | 0.75 | TSHR (0.53) | MAPTLMNAALDH1A1SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345847-B1 | PROCESS FOR THE PREPARATION OF POLYMERS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-08-04 | — | — | EP | disclosed |
| EP-0345847-A1 | Process for the preparation of polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-12-13 | — | — | EP | disclosed |