SCHEMBL7750244

SCHEMBL7750244

CCSc1ccc(N)c(C)c1N

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.37
RAB9A P51151 2/20 0.37
CYP3A4 P08684 2/20 0.36
TSHR P16473 1/20 0.36
PIK3CA P42336 1/20 0.36
ALOX15 P16050 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TP53 P04637 1/20 0.33
THRB P10828 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
AOC3 Q16853 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
SLC6A2 P23975 2/20 0.31
SLC6A4 P31645 2/20 0.31
SLC6A3 Q01959 2/20 0.31
HSP90AA1 P07900 1/20 0.31
ALDH1A1 P00352 3/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9009906 0.84 PTGS2 (0.37) NPC1RAB9ACYP3A4TSHRPIK3CA
SCHEMBL9131932 0.80 AOC3 (0.32) AOC3
SCHEMBL8763695 0.79 AOC3 (0.33) NPC1AOC3MEN1KMT2AAPOBEC3G
SCHEMBL26909710 0.77 POLB (0.38) NPC1RAB9ACYP3A4SMN1; SMN2AOC3
SCHEMBL8764598 0.76 NPC1 (0.32) NPC1RAB9AAOC3MEN1KMT2A
SCHEMBL2860505 0.76 NPC1 (0.45) NPC1RAB9ACYP3A4TSHRPIK3CA
SCHEMBL48321 0.76 AOC3 (0.36) AOC3HSP90AA1ALDH1A1MAPT
SCHEMBL14219137 0.75 NPC1 (0.55) NPC1RAB9ACYP3A4TSHRALOX15
SCHEMBL9076489 0.74 AOC3 (0.32) NPC1AOC3MEN1KMT2AAPOBEC3G
SCHEMBL17033346 0.72 ALDH1A1 (0.45) NPC1RAB9ACYP3A4SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4153647-A1 POLYUREA COMPOSITION WITH A LOW CONTENT IN MONOMERIC DIISOCYANTES Sika Technology AG (CH) 2023-03-29 EP claimed
WO-2001039844-A1 GOLF BALL COMPRISING WATER RESISTANT POLYURETHANE ELASTOMERS AND METHODS OF MAKING THE SAME ACUSHNET COMPANY (US) 2001-06-07 WO claimed
EP-3036265-A1 POLYURETHANE ELASTOMERIC SEAL FOR HYDRAULIC PUMPS Dow Global Technologies LLC (US) 2016-06-29 EP disclosed
US-20160130466-A1 CURATIVE AGENT FOR COATINGS ON INDUSTRIAL ROLLERS DOW GLOBAL TECHNOLOGIES LLC (US) 2016-05-12 US disclosed
EP-3013878-A1 CURATIVE AGENT FOR COATINGS ON INDUSTRIAL ROLLERS Dow Global Technologies LLC (US) 2016-05-04 EP disclosed
US-9096707-B2 Elastomers for paper mill equipment DOW GLOBAL TECHNOLOGIES LLC (US) 2015-08-04 US disclosed
WO-2015026613-A1 POLYURETHANE ELASTOMERIC SEAL FOR HYDRAULIC PUMPS DOW GLOBAL TECHNOLOGIES LLC (US) 2015-02-26 WO disclosed
WO-2014210103-A1 CURATIVE AGENT FOR COATINGS ON INDUSTRIAL ROLLERS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-31 WO disclosed
EP-2814860-A1 ELASTOMERS FOR PAPER MILL EQUIPMENT Dow Global Technologies LLC (US) 2014-12-24 EP disclosed
US-20140352904-A1 ELASTOMERS FOR PAPER MILL EQUIPMENT DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-04 US disclosed
WO-2013122812-A1 ELASTOMERS FOR PAPER MILL EQUIPMENT DOW GLOBAL TECHNOLOGIES LLC (US) 2013-08-22 WO disclosed
EP-1159082-A4 BITUMINOUS POLYURETHANE INTERPENETRATING ELASTOMERIC NETWORK COMPOSITIONS URECOATS TECHNOLOGIES INC (US) 2001-12-12 EP disclosed
WO-2001091551-A1 POLYURETHANE/POLYUREA MATRICES FOR THE DELIVERY OF ACTIVE AGENTS FLAVOR & FRAGRANCE SPECIALTIES (US) 2001-12-06 WO disclosed
EP-1159082-A2 BITUMINOUS POLYURETHANE INTERPENETRATING ELASTOMERIC NETWORK COMPOSITIONS Urecoats Technologies, Inc. (US) 2001-12-05 EP disclosed
WO-2000011111-A2 BITUMINOUS POLYURETHANE INTERPENETRATING ELASTOMERIC NETWORK COMPOSITIONS URECOATS INTERNATIONAL, INC. (US) 2000-03-02 WO disclosed